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I-XW-053

I-XW-053 is a small-molecule inhibitor designed to disrupt HIV-1 capsid assembly by targeting the N-terminal domain (NTD-NTD) interface with micromolar affinity. It serves as a valuable chemical probe for studying capsid protein (CA) interactions and viral replication mechanisms in both in vitro biochemical and cell-based antiviral assays.

Product Specifications

CAS Number

5496-35-5

Product Name Alternative

I-XW 053, IXW053, I-XW053, I-XW-053, I XW 053, HIVProtease, HIV Protease, HIV-1

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Purity

99.05% (May vary between batches)

Solubility

DMSO:50 mg/mL (146.9 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (14.69 mM)

Smiles

OC (=O) c1ccc (cc1) -c1nc (c ([nH]1) -c1ccccc1) -c1ccccc1

Molecular Formula

C22H16N2O2

Molecular Weight

340.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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