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8-Azahypoxanthine

8-Azahypoxanthine is a purine analog that acts as an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) . This mechanism underlies its studied antimalarial activity, as it disrupts purine salvage in Plasmodium parasites. It serves as a research tool for investigating nucleotide metabolism in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2683-90-1

Product Name Alternative

NSC22709, NSC-22709, NSC 22709, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, Nucleoside Antimetabolite, 8 Azahypoxanthine, 8Azahypoxanthine, 8-Azahypoxanthine, Analog

Field of Research

Cell Biology, Molecular Biology

Purity

≥98% (May vary between batches)

Solubility

DMSO:55 mg/mL (401.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (14.59 mM)

Smiles

O=C1N=CNC2=NNN=C12

Molecular Formula

C4H3N5O

Molecular Weight

137.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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