8-Azahypoxanthine
8-Azahypoxanthine is a purine analog that acts as an inhibitor of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) . This mechanism underlies its studied antimalarial activity, as it disrupts purine salvage in Plasmodium parasites. It serves as a research tool for investigating nucleotide metabolism in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2683-90-1
Product Name Alternative
NSC22709, NSC-22709, NSC 22709, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, Nucleoside Antimetabolite, 8 Azahypoxanthine, 8Azahypoxanthine, 8-Azahypoxanthine, Analog
Field of Research
Cell Biology, Molecular Biology
Purity
≥98% (May vary between batches)
Solubility
DMSO:55 mg/mL (401.17 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (14.59 mM)
Smiles
O=C1N=CNC2=NNN=C12
Molecular Formula
C4H3N5O
Molecular Weight
137.1
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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