Oclacitinib
Oclacitinib (PF-03394197) is a potent and selective Janus kinase (JAK) inhibitor, demonstrating IC50 values in the 10-99 nM range against JAK family enzymes while showing high selectivity over 38 other kinases (IC50 >1000 nM) . It is widely used in preclinical research for investigating JAK-mediated pathways in immunological and inflammatory diseases, with applications in both in vitro cellular assays and in vivo animal models.
Product Specifications
CAS Number
1208319-26-9
Product Name Alternative
Oclacitinib, JAKs, PF 03394197, PF03394197, PF-03394197
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.71% (May vary between batches)
Solubility
DMSO:55 mg/mL (162.99 mM)
Smiles
CNS (=O) (=O) C[C@H]1CC[C@@H] (CC1) N (C) c1ncnc2[nH]ccc12
Molecular Formula
C15H23N5O2S
Molecular Weight
337.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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