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Ponalrestat

Ponalrestat is a selective aldose reductase inhibitor used in research to investigate diabetic complications. It is applied in both in vitro enzyme assays and in vivo animal models to study pathways involving neuropathy, retinopathy, and nephropathy.

Product Specifications

CAS Number

72702-95-5

Product Name Alternative

Ponalrestat, sorbitol, inhibit, noncompetitive, orally, Inhibitor, ICI 128436, ICI128436, ICI-128436, glucose, ALR1, ALR, ALR2, Aldose Reductase, Aldose reductase, AKR1B1, conversion

Field of Research

Metabolism Research

Purity

97.34% (May vary between batches)

Solubility

DMSO:45 mg/mL (115.03 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (5.11 mM)

Smiles

OC (=O) Cc1nn (Cc2ccc (Br) cc2F) c (=O) c2ccccc12

Molecular Formula

C17H12BrFN2O3

Molecular Weight

391.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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