MLN9708 analogues
MLN2238, the biologically active form of Ixazomib (MLN9708), is a potent and selective inhibitor of the 20S proteasome's chymotrypsin-like (β5) activity (Ki50=0.93 nM, IC50=3.4 nM) . This investigational small molecule is widely used in preclinical research, including in vitro cell-based assays and in vivo xenograft models, to study proteasome function and cancer therapeutics.
Product Specifications
CAS Number
1201902-80-8
Product Name Alternative
20S proteasome, MLN9708, MLN-9708, MLN 9708, Ixazomib Citrate analogues
Field of Research
Cell Biology, Protein Biochemistry
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.38 mM) ; DMSO:93 mg/mL (179.84 mM)
Smiles
CC (C) C[C@H] (NC (=O) CNC (=O) c1cc (Cl) ccc1Cl) B1OC (=O) CC (CC (O) =O) (O1) C (O) =O
Molecular Formula
C20H23BCl2N2O9
Molecular Weight
517.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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