Tiplaxtinin
Tiplaxtinin (PAI-039) is a potent, selective, and orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), exhibiting an IC50 of 2.7 μM. It is a valuable research tool for studying fibrinolysis, thrombosis, and fibrosis in both cellular assays and animal models.
Product Specifications
CAS Number
393105-53-8
Product Name Alternative
Plasminogen activator inhibitor-1, Tiplasinin, Tiplaxtinin, Inhibitor, inhibit, PAI-1, PAI1, PAI039, PAI-039, PAI 039, Apoptosis
Field of Research
Cell Biology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.55 mM) ; DMSO:50 mg/mL (113.8 mM) ; Ethanol:15 mg/mL (34.14 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) C (=O) c1cn (Cc2ccccc2) c2ccc (cc12) -c1ccc (OC (F) (F) F) cc1
Molecular Formula
C24H16F3NO4
Molecular Weight
439.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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