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Tiplaxtinin

Tiplaxtinin (PAI-039) is a potent, selective, and orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), exhibiting an IC50 of 2.7 μM. It is a valuable research tool for studying fibrinolysis, thrombosis, and fibrosis in both cellular assays and animal models.

Product Specifications

CAS Number

393105-53-8

Product Name Alternative

Plasminogen activator inhibitor-1, Tiplasinin, Tiplaxtinin, Inhibitor, inhibit, PAI-1, PAI1, PAI039, PAI-039, PAI 039, Apoptosis

Field of Research

Cell Biology, Metabolism Research

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.55 mM) ; DMSO:50 mg/mL (113.8 mM) ; Ethanol:15 mg/mL (34.14 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

OC (=O) C (=O) c1cn (Cc2ccccc2) c2ccc (cc12) -c1ccc (OC (F) (F) F) cc1

Molecular Formula

C24H16F3NO4

Molecular Weight

439.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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