AG1557
AG1557 is a potent and selective EGFR tyrosine kinase inhibitor with a pIC50 of 8.194. This small molecule is used in biochemical and cellular assays to study EGFR-driven signaling pathways in cancer research, including investigations into cell proliferation and tumor growth.
Product Specifications
CAS Number
189290-58-2
Product Name Alternative
Inhibit, EGFR, Epidermal growth factor receptor, ErbB-1, Inhibitor, HER1, hERG, AG 1557, AG1557, AG-1557
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.46 mM) ; DMSO:4.08 mg/mL (10.02 mM)
Smiles
COc1cc2ncnc (Nc3cccc (I) c3) c2cc1OC
Molecular Formula
C16H14IN3O2
Molecular Weight
407.21
Storage Conditions
-20°C
Notes
For research use only.
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