6-OAU
6-OAU (GTPL5846) is a potent and selective synthetic agonist for the GPR84 receptor. It demonstrates an EC50 of 105 nM in Gqi5-coupled in vitro phosphatidylinositol (PI) assays using HEK293 cells. This tool compound is valuable for investigating GPR84's role in immune and metabolic functions in both cellular and animal models.
Product Specifications
CAS Number
83797-69-7
Product Name Alternative
Chemotaxis, Cytokines, 6 OAU, 6OAU, 6-OAU, B. abortus, macrophage, Inhibitor, inhibit, inflammation, IL-8, ERK, Extracellular signal regulated kinases, GTPL 5846, GTPL5846, GTPL-5846, GTPγS, GPR84, G protein-coupled receptor, G protein coupled receptor 84, Lauric acid, MAPKs, HEK293, rat air pouch model, Sf9, PMN, proinflammatory cytokine, TNF-α, U937
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.14% (May vary between batches)
Solubility
DMSO:55 mg/mL (229.83 mM)
Smiles
CCCCCCCCNc1cc (=O) [nH]c (=O) [nH]1
Molecular Formula
C12H21N3O2
Molecular Weight
239.31
Storage Conditions
-20°C
Notes
For research use only.
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