RG-108
RG108 (N-Phthalyl-L-tryptophan) is a potent and cell-permeable inhibitor of DNA methyltransferases with an IC50 of 115 nM. It is widely used in epigenetic research to reactivate silenced genes and has been applied in both cellular and animal studies to investigate DNA methylation's role in development and disease.
Product Specifications
CAS Number
48208-26-0
Product Name Alternative
N-Phthalyl-L-tryptophan
Field of Research
Epigenetics & Chromatin, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
DNA methyltransferase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml) .
Smiles
[C@H] (CC=1C=2C (NC1) =CC=CC2) (C (O) =O) N3C (=O) C=4C (C3=O) =CC=CC4
Molecular Formula
C19H14N2O4
Molecular Weight
334.34
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(S) -2- (1,3-dioxoisoindolin-2-yl) -3- (1H-indol-3-yl) propanoic acid
Available Sizes
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