AG-1517 HCl
PD153035 hydrochloride is a potent and highly selective EGFR inhibitor with a Ki of 5.2 pM. It exhibits minimal activity against FGFR, PDGFR, InsR, CSF-1R, and Src. This compound is widely used in cancer research to study EGFR-driven signaling pathways in both cellular and animal models.
Product Specifications
CAS Number
153436-54-5
Product Name Alternative
PD153,053; SU-5271; Z-252868
Field of Research
Cardiovascular Research, Signal Transduction
Purity
>98%
Bioactivity
EGFR Tyrosine kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml) .
Smiles
COC1=CC2=NC=NC (NC3=CC (Br) =CC=C3) =C2C=C1OC
Molecular Formula
C16H14BrN3O2
Molecular Weight
360.21
Storage Conditions
RT
Notes
For research use only.
Other Product Names
4- (3-Bromoanilino) -6,7-dimethoxyquinazoline hydrochloride
Available Sizes
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