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Mutant IDH1-IN-1

Mutant IDH1-IN-1 is a highly potent small molecule inhibitor targeting the R132H mutant IDH1 enzyme, demonstrating an IC50 value below 0.1 μM. It is a valuable research tool for investigating mutant IDH1-driven mechanisms in cancers such as glioma and AML, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1355326-21-4

Product Name Alternative

Isocitrate Dehydrogenase, IsocitrateDehydrogenase (IDH), Isocitrate Dehydrogenase (IDH), IsocitrateDehydrogenase, Mutant IDH1 IN 1, mutant IDH1 R132H, Mutant IDH1IN1, Mutant IDH-1-IN-1, Mutant IDH1-IN-1, IDH, IDH1-IN-1

Field of Research

Metabolism Research

Purity

98.98% (May vary between batches)

Solubility

DMSO:60 mg/mL (120.34 mM)

Smiles

Cc1ccccc1C (N (C (=O) Cn1cnc2ccccc12) c1cccc (F) c1) C (=O) NC1CCCCC1

Molecular Formula

C30H31FN4O2

Molecular Weight

498.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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