Mutant IDH1-IN-1
Mutant IDH1-IN-1 is a highly potent small molecule inhibitor targeting the R132H mutant IDH1 enzyme, demonstrating an IC50 value below 0.1 μM. It is a valuable research tool for investigating mutant IDH1-driven mechanisms in cancers such as glioma and AML, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1355326-21-4
Product Name Alternative
Isocitrate Dehydrogenase, IsocitrateDehydrogenase (IDH), Isocitrate Dehydrogenase (IDH), IsocitrateDehydrogenase, Mutant IDH1 IN 1, mutant IDH1 R132H, Mutant IDH1IN1, Mutant IDH-1-IN-1, Mutant IDH1-IN-1, IDH, IDH1-IN-1
Field of Research
Metabolism Research
Purity
98.98% (May vary between batches)
Solubility
DMSO:60 mg/mL (120.34 mM)
Smiles
Cc1ccccc1C (N (C (=O) Cn1cnc2ccccc12) c1cccc (F) c1) C (=O) NC1CCCCC1
Molecular Formula
C30H31FN4O2
Molecular Weight
498.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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