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AG-1478

AG-1478 (Tyrphostin AG-1478, NSC-693255) is a potent and selective inhibitor of the Epidermal Growth Factor Receptor (EGFR) . It is widely used in biochemical and cell-based research to study EGFR-driven signaling pathways, proliferation, and tumorigenesis in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

153436-53-4

Product Name Alternative

PDGFR, virus, Tyrphostin AG1478, Tyrphostin AG-1478, Tyrphostin AG 1478, HCV, HCVProtease, HCV Protease, Hepatitis C virus, HER1, HER2, Inhibitor, injury, EGFR, encephalomyocarditis, EMCV, Epidermal growth factor receptor, ErbB-1, inhibit, NSC 693255, InfluenzaVirus, Influenza Virus, myocardial, NSC693255, NSC-693255, obesity, cancer, cardiovascular, antiviral, AG1478, AG-1478, AG 1478, chemotherapy, diseases

Field of Research

Cardiovascular Research, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Purity

99.03% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.17 mM) ; DMSO:10 mg/mL (31.67 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

N (C=1C2=C (C=C (OC) C (OC) =C2) N=CN1) C3=CC (Cl) =CC=C3

Molecular Formula

C16H14ClN3O2

Molecular Weight

315.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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