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LY364947

LY-364947 (HTS466284) is a selective, ATP-competitive small molecule inhibitor targeting the TGF-β type I receptor kinase (ALK5) . It is widely utilized in biochemical and cellular assays to investigate TGF-β signaling pathways in cancer, fibrosis, and developmental biology research, demonstrating activity in both in vitro and in vivo models.

Product Specifications

CAS Number

396129-53-6

Product Name Alternative

HTS-466284

Field of Research

Immunology & Inflammation, Neuroscience, Stem Cell & Developmental Biology

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (75 mg/ml)

Smiles

N1C=C (C (=N1) C1=NC=CC=C1) C1=CC=NC2=CC=CC=C12

Molecular Formula

C17H12N4

Molecular Weight

272.3

Storage Conditions

RT

Notes

For research use only.

Other Product Names

4- (3-Pyridin-2-yl-1H-pyrazol-4-yl) quinolone

Available Sizes

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