LY364947
LY-364947 (HTS466284) is a selective, ATP-competitive small molecule inhibitor targeting the TGF-β type I receptor kinase (ALK5) . It is widely utilized in biochemical and cellular assays to investigate TGF-β signaling pathways in cancer, fibrosis, and developmental biology research, demonstrating activity in both in vitro and in vivo models.
Product Specifications
CAS Number
396129-53-6
Product Name Alternative
HTS-466284
Field of Research
Immunology & Inflammation, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (75 mg/ml)
Smiles
N1C=C (C (=N1) C1=NC=CC=C1) C1=CC=NC2=CC=CC=C12
Molecular Formula
C17H12N4
Molecular Weight
272.3
Storage Conditions
RT
Notes
For research use only.
Other Product Names
4- (3-Pyridin-2-yl-1H-pyrazol-4-yl) quinolone
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