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DMH-1

DMH-1 is a selective small molecule BMP inhibitor targeting ALK1, ALK2, ALK3, and ALK6. It is widely used in stem cell research to direct the differentiation of pluripotent stem cells in vitro and has been applied in studies of bone development and heterotopic ossification in vivo.

Product Specifications

CAS Number

1206711-16-1

Product Name Alternative

DMH 1, DMH1, DMH-1, ALK2, Autophagy, Inhibitor, inhibit, TGFbeta, TGF-b/Smad, TGFb, TGFβ, TGF-β/Smad, TGF-β Receptor, TGF-beta, TGFbeta/Smad, Smad, Transforming growth factor beta receptors

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1.25 mg/mL (3.29 mM) ; DMSO:12.68 mg/mL (33.33 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CC (C) Oc1ccc (cc1) -c1cnc2c (cnn2c1) -c1ccnc2ccccc12

Molecular Formula

C24H20N4O

Molecular Weight

380.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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