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LDN-214117

LDN-214117 is a selective small molecule inhibitor targeting the ALK2 kinase. It is utilized in research to investigate pathways involving bone morphogenetic proteins (BMPs), with applications in both cellular studies and animal models of fibrodysplasia ossificans progressiva (FOP) and other disorders.

Product Specifications

CAS Number

1627503-67-6

Product Name Alternative

ALK3, ALK2, ALK5, ALK1, bone morphogenetic proteins (BMPs), BMP6, BMP4, BMP2, diffuse intrinsic pontine glioma (DIPG), oral, fibrodysplasia ossificans progressiva (FOP), LDN 214117, LDN214117, LDN-214117, Transforming growth factor beta receptors, TGFβ, TGFbeta/Smad, TGF-β Receptor, TGF-β/Smad, TGF-b/Smad, TGFb, TGFbeta, TGF-beta, Smad, type I receptor kinases

Field of Research

Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

DMSO:4.2 mg/mL (10.01 mM) ; Ethanol:42 mg/mL (100.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.38 mM)

Smiles

COc1cc (cc (OC) c1OC) -c1cc (cnc1C) -c1ccc (cc1) N1CCNCC1

Molecular Formula

C25H29N3O3

Molecular Weight

419.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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