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N1-Methylpseudouridine

N1-Methylpseudouridine is a modified nucleoside that augments mRNA translation by boosting ribosome density through both eIF2α-dependent and independent pathways. It is widely used in mRNA vaccine research and therapeutic development to enhance protein expression in both in vitro and in vivo systems.

Product Specifications

CAS Number

13860-38-3

Product Name Alternative

Ribosome, protein, polysomes, phosphorylation, 1-Methylpseudouridine, cells, DNA/RNA Synthesis, Nucleoside Antimetabolite/Analog, N1 Methylpseudouridine, N1Methylpseudouridine, N-1-Methylpseudouridine, N1-Methylpseudouridine, inhibit, mRNA, GFP, eIF2α, expression, HEK293T, Inhibitor

Field of Research

Cell Biology, Molecular Biology

Purity

98.95% (May vary between batches)

Solubility

H2O:40 mg/mL (154.9 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.49 mM) ; DMSO:100 mg/mL (387.25 mM)

Smiles

Cn1cc ([C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2O) c (=O) [nH]c1=O

Molecular Formula

C10H14N2O6

Molecular Weight

258.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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