AZD4547
AZD4547 is a potent and selective FGFR family inhibitor, suppressing cancer cell proliferation by blocking FGFR1-3 phosphorylation with low nanomolar IC50 values. It is widely used in preclinical research to study FGFR-driven tumor models both in vitro and in vivo, supporting investigations in oncology and targeted therapy development.
Product Specifications
CAS Number
1035270-39-3
Product Name Alternative
Inhibit, Inhibitor, KDR, Fibroblast growth factor receptor, FGFR4, FGFR, FGFR1, FGFR2, FGFR3, AZD4547, AZD-4547, AZD 4547
Field of Research
Cardiovascular Research, Signal Transduction
Purity
>98%
Bioactivity
FGFR 1,2,3 inhibitor
Form
Powder
Solubility
DMSO:252.5 mg/mL (544.69 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.39 mM)
Smiles
COc1cc (CCc2cc (NC (=O) c3ccc (cc3) N3C[C@H] (C) N[C@H] (C) C3) n[nH]2) cc (OC) c1
Molecular Formula
C26H33N5O3
Molecular Weight
463.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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