MK-2206
MK-2206 2HCl is a potent, selective, and orally bioavailable allosteric inhibitor of Akt isoforms (Akt1/2/3) . It demonstrates antitumor efficacy in preclinical models and is utilized in cancer research for studying PI3K/Akt signaling in both cellular and animal studies.
Product Specifications
CAS Number
1032350-13-2
Product Name Alternative
Breast, Akt, Autophagy, Akt2, Akt3, Akt1, Apoptosis, cancer, oral, MK 2206, MK 2206 Dihydrochloride, MK 2206 dihydrochloride, MK2206, MK-2206, MK-2206 (2HCl), MK-2206 2HCl, MK2206 dihydrochloride, MK2206 Dihydrochloride, MK-2206 Dihydrochloride, Inhibitor, inhibit, loss, mutant, PIK3CA, PKB, sensitive, selective, Protein kinase B, PTEN
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Akt inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml with warming)
Smiles
Cl.Cl.NC1 (CCC1) c1ccc (cc1) -c1nc2ccn3c (n[nH]c3=O) c2cc1-c1ccccc1
Molecular Formula
C25H21N5O·2HCl
Molecular Weight
480.39
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
8- (4- (1-Aminocyclobutyl) phenyl-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one dihydrochloride
Available Sizes
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