AZ20
AZ20 is a potent and selective ATR kinase inhibitor with an IC50 of 5 nM, demonstrating 8-fold selectivity over mTOR. This small molecule is a valuable chemical probe for investigating DNA damage response pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
1233339-22-4
Product Name Alternative
ATR, AZ 20, Ataxia telangiectasia mutated, ATM, ATM and RAD3 related, ATM/ATR, AZ20, AZ-20, Inhibitor, inhibit, mTOR
Field of Research
Cell Biology
Purity
>98%
Bioactivity
ATR Kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
C[C@@H]1COCCN1c1cc (nc (n1) -c1cccc2[nH]ccc12) C1 (CC1) S (C) (=O) =O
Molecular Formula
C21H24N4O3S
Molecular Weight
412.51
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-{4-[ (3R) -3-Methyl-4-morpholinyl]-6-[1- (methylsulfonyl) cyclopropyl]-2-pyrimidinyl}-1H-indole
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