BIX-01294 trihydrochloride
BIX-01294 trihydrochloride is a cell-permeable, potent, and selective inhibitor of the G9a histone methyltransferase, exhibiting an IC50 of 2.7 μM in biochemical assays. It is widely used in epigenetics research to probe the role of histone H3 lysine 9 methylation in gene silencing, cellular differentiation, and has been applied in both cellular and animal studies.
Product Specifications
CAS Number
1392399-03-9
Product Name Alternative
Cdkn1a, Autophagy, BIX 01294, BIX01294, BIX-01294, H3K9me2, H3K9me3, G9a, Gadd45a, HistoneMethyltransferase, Histone Methyltransferase, p53, MLKL, p21, SUV39H1 (H320R), recurrent, PRMT1
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.98% (May vary between batches)
Solubility
DMSO:260 mg/mL (433.32 mM) ; H2O:60 mg/mL (100 mM)
Smiles
Cl.Cl.Cl.COc1cc2nc (nc (NC3CCN (Cc4ccccc4) CC3) c2cc1OC) N1CCCN (C) CC1
Molecular Formula
C28H38N6O2·3HCl
Molecular Weight
600.02
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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