Tubastatin A
Tubastatin A is a potent and highly selective HDAC6 inhibitor, exhibiting an IC50 of 15 nM in biochemical assays with >1000-fold selectivity over other HDAC isoforms except HDAC8. It is widely used in both in vitro and in vivo research to investigate HDAC6's role in oncology, neurology, and immunology, including studies on neurodegenerative disease models and cancer cell proliferation.
Product Specifications
CAS Number
1252003-15-8
Product Name Alternative
Tubastatin A, Tubastatin A BASE, Apoptosis, Autophagy, HDAC, HDAC6, Histone deacetylases
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology
Purity
97.22% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:35 mg/mL (104.35 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.98 mM)
Smiles
CN1CCc2c (C1) c1ccccc1n2Cc1ccc (cc1) C (=O) NO
Molecular Formula
C20H21N3O2
Molecular Weight
335.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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