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Tubastatin A

Tubastatin A is a potent and highly selective HDAC6 inhibitor, exhibiting an IC50 of 15 nM in biochemical assays with >1000-fold selectivity over other HDAC isoforms except HDAC8. It is widely used in both in vitro and in vivo research to investigate HDAC6's role in oncology, neurology, and immunology, including studies on neurodegenerative disease models and cancer cell proliferation.

Product Specifications

CAS Number

1252003-15-8

Product Name Alternative

Tubastatin A, Tubastatin A BASE, Apoptosis, Autophagy, HDAC, HDAC6, Histone deacetylases

Field of Research

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology

Purity

97.22% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:35 mg/mL (104.35 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.98 mM)

Smiles

CN1CCc2c (C1) c1ccccc1n2Cc1ccc (cc1) C (=O) NO

Molecular Formula

C20H21N3O2

Molecular Weight

335.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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