SCH-37370
SCH-37370 is an orally active dual antagonist of platelet-activating factor (PAF) and histamine H1 receptors. It effectively inhibits PAF-induced human platelet aggregation and blocks histamine binding in rat brain membranes, making it a useful research tool for studying inflammation and allergic responses in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
117796-52-8
Product Name Alternative
Platelet-activating factor (PAF), Platelet aggregation, Plateletaggregation, SCH 37370, SCH37370, SCH-37370
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.07% (May vary between batches)
Solubility
DMSO:30 mg/mL (85.02 mM)
Smiles
ClC=1C=C2C (C (C=3C (CC2) =CC=CN3) =C4CCN (C (C) =O) CC4) =CC1
Molecular Formula
C21H21ClN2O
Molecular Weight
352.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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