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Gedatolisib

Gedatolisib (PF-05212384) is a potent dual inhibitor of PI3Kα/γ and mTOR, with IC50 values of 0.4/5.4 nM and 1.6 nM, respectively. It is widely used in preclinical research to study oncogenic signaling and has demonstrated antitumor activity in both cellular assays and in vivo cancer models.

Product Specifications

CAS Number

1197160-78-3

Product Name Alternative

MTOR, inhibit, Gedatolisib, Inhibitor, Mammalian target of Rapamycin, PF 05212384, PF05212384, PF-05212384, PKI 587, PKI587, PKI-587, PI3Kγ, PI3K, PI3Kα, Phosphoinositide 3-kinase

Field of Research

Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:10 mg/mL (16.24 mM)

Smiles

N (C (NC1=CC=C (C (=O) N2CCC (N (C) C) CC2) C=C1) =O) C3=CC=C (C=4N=C (N=C (N4) N5CCOCC5) N6CCOCC6) C=C3

Molecular Formula

C32H41N9O4

Molecular Weight

615.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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