Gedatolisib
Gedatolisib (PF-05212384) is a potent dual inhibitor of PI3Kα/γ and mTOR, with IC50 values of 0.4/5.4 nM and 1.6 nM, respectively. It is widely used in preclinical research to study oncogenic signaling and has demonstrated antitumor activity in both cellular assays and in vivo cancer models.
Product Specifications
CAS Number
1197160-78-3
Product Name Alternative
MTOR, inhibit, Gedatolisib, Inhibitor, Mammalian target of Rapamycin, PF 05212384, PF05212384, PF-05212384, PKI 587, PKI587, PKI-587, PI3Kγ, PI3K, PI3Kα, Phosphoinositide 3-kinase
Field of Research
Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:10 mg/mL (16.24 mM)
Smiles
N (C (NC1=CC=C (C (=O) N2CCC (N (C) C) CC2) C=C1) =O) C3=CC=C (C=4N=C (N=C (N4) N5CCOCC5) N6CCOCC6) C=C3
Molecular Formula
C32H41N9O4
Molecular Weight
615.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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