RN486
RN486 is a potent and selective small molecule inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 4 nM. It is a valuable research tool for investigating B-cell receptor signaling in immunological and oncological studies, applicable in both cellular assays and in vivo disease models.
Product Specifications
CAS Number
1242156-23-5
Product Name Alternative
Bruton tyrosine kinase, BTK, Btk, inhibit, Inhibitor, RN486, RN-486, RN 486
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.38% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:58 mg/mL (95.6 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN1CCN (CC1) c1ccc (Nc2cc (cn (C) c2=O) -c2cccc (c2CO) -n2ccc3cc (cc (F) c3c2=O) C2CC2) nc1
Molecular Formula
C35H35FN6O3
Molecular Weight
606.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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