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Dorsomorphin

Dorsomorphin (BML-275) is a selective, ATP-competitive AMPK inhibitor (Ki=109 nM) that also blocks BMP receptors ALK2, ALK3, and ALK6. It is widely used in research to study autophagy, bone morphogenetic protein signaling, and tumor biology in both cellular and animal models due to its antitumor properties.

Product Specifications

CAS Number

866405-64-3

Product Name Alternative

Compound C

Field of Research

Cell Biology, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

AMPK inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 3 mg/ml) .

Smiles

C (CN1CCCCC1) Oc1ccc (cc1) -c1cnc2c (cnn2c1) -c1ccncc1

Molecular Formula

C24H25N5O

Molecular Weight

399.49

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

6-[4-[2- (1-Piperidinyl) ethoxy]phenyl]-3- (4-pyridinyl) -pyrazolo[1,5-a]pyrimidine

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