B-Raf IN 11
B-Raf IN 11 is a novel, selective inhibitor that preferentially targets the DFG-in conformation of the B-Raf V600E mutant kinase. This compound is a valuable research tool for investigating colorectal cancer mechanisms and evaluating therapeutic strategies in both cellular and animal models of the disease.
Product Specifications
CAS Number
918504-27-5
Product Name Alternative
B-Raf (V600E), B-Raf IN 11, ZINC72115182, ZINC-72115182
Field of Research
Signal Transduction
Purity
99.46% (May vary between batches)
Solubility
DMSO:60 mg/mL (130.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM)
Smiles
C (=O) (C=1C=2C (NC1) =NC=C (Br) C2) C3=C (F) C (NS (CCC) (=O) =O) =CC=C3F
Molecular Formula
C17H14BrF2N3O3S
Molecular Weight
458.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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