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3-AP

3-AP (Triapine) is a potent and selective small molecule inhibitor targeting the ribonucleotide reductase M2 subunit (RRM2) . It has been widely used in vitro and in vivo research to study DNA synthesis inhibition, cell cycle arrest, and as a chemotherapeutic agent in experimental oncology models.

Product Specifications

CAS Number

143621-35-6

Product Name Alternative

DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, 3 AP, 3AP, 3-AP, NSC663249, NSC-663249, OCX 191, OCX191, OCX-191, NSC 663249, NSC# 663249, PAN 811, PAN811, PAN-811, Inhibitor, inhibit, RNA Synthesis, RNASynthesis, RR, Triapine

Field of Research

Cell Biology, Molecular Biology

Purity

97.33% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.24 mM) ; DMSO:50 mg/mL (256.1 mM)

Smiles

NC (=S) N\N=C\c1ncccc1N

Molecular Formula

C7H9N5S

Molecular Weight

195.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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