3-AP
3-AP (Triapine) is a potent and selective small molecule inhibitor targeting the ribonucleotide reductase M2 subunit (RRM2) . It has been widely used in vitro and in vivo research to study DNA synthesis inhibition, cell cycle arrest, and as a chemotherapeutic agent in experimental oncology models.
Product Specifications
CAS Number
143621-35-6
Product Name Alternative
DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, 3 AP, 3AP, 3-AP, NSC663249, NSC-663249, OCX 191, OCX191, OCX-191, NSC 663249, NSC# 663249, PAN 811, PAN811, PAN-811, Inhibitor, inhibit, RNA Synthesis, RNASynthesis, RR, Triapine
Field of Research
Cell Biology, Molecular Biology
Purity
97.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.24 mM) ; DMSO:50 mg/mL (256.1 mM)
Smiles
NC (=S) N\N=C\c1ncccc1N
Molecular Formula
C7H9N5S
Molecular Weight
195.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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