Parmodulin 2
Parmodulin-2 (ML 161) is a selective small-molecule antagonist of protease-activated receptor 1 (PAR1), inhibiting thrombin-induced platelet activation and P-selectin expression (IC50 = 0.26 μM) . It is a valuable research tool for studying thrombosis and inflammation in both in vitro cellular assays and in vivo animal models of vascular disease.
Product Specifications
CAS Number
423735-93-7
Product Name Alternative
Aggregation, ML 161, ML161, ML-161, Parmodulin 2, Parmodulin2, Parmodulin-2, PAR-1, PAR1, inhibit, Inhibitor, formation, P-selectin, Protease Activated Receptor (PAR), ProteaseactivatedReceptor, Proteaseactivated Receptor, Protease-Activated Receptor (PAR), protease-activated, platelet, Thrombin receptors, thrombus, receptor, SFLLRN-induced
Field of Research
Pharmacology & Drug Discovery
Purity
96.72% (May vary between batches)
Solubility
DMSO:36.1 mg/mL (99.94 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.54 mM) ; Ethanol:36.1 mg/mL (99.94 mM)
Smiles
CCCC (=O) Nc1cccc (NC (=O) c2ccccc2Br) c1
Molecular Formula
C17H17BrN2O2
Molecular Weight
361.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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