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RKI-1447

RKI-1447 is a selective small molecule inhibitor targeting ROCK1 and ROCK2 kinases. It demonstrates anti-invasive and anti-tumor properties, making it a valuable research tool for studying cancer cell migration, metastasis, and tumor progression in both cellular and animal models.

Product Specifications

CAS Number

1342278-01-6

Product Name Alternative

RKI 1447, RKI1447, RKI-1447, ROCK, ROCK1, ROCK2, ROK, Rho-kinase, Rho-associated kinase, Rho-associated protein kinase, inhibit, Inhibitor

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.13 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:18.33 mg/mL (56.16 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Oc1cccc (CNC (=O) Nc2nc (cs2) -c2ccncc2) c1

Molecular Formula

C16H14N4O2S

Molecular Weight

326.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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