Afuresertib
Afuresertib (GSK2110183) is an orally active, small-molecule inhibitor targeting the Akt kinase. It is utilized in oncology research to investigate Akt-driven signaling pathways and has demonstrated antitumor activity in both cellular assays and animal models of various cancers.
Product Specifications
CAS Number
1047644-62-1
Product Name Alternative
Afuresertib, Akt, Akt3, Akt2, Akt1, inhibit, Inhibitor, GSK 2110183, GSK2110183, GSK-2110183, GSK2110183C, Rho-associated kinase, Rho-associated protein kinase, ROCK, ROK, Rho-kinase, PKB, PKC, Protein kinase C, Protein kinase B
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.51% (May vary between batches)
Solubility
DMSO:50 mg/mL (117.01 mM) ; Ethanol:79 mg/mL (184.87 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.68 mM)
Smiles
Cn1ncc (Cl) c1-c1cc (sc1Cl) C (=O) N[C@H] (CN) Cc1cccc (F) c1
Molecular Formula
C18H17Cl2FN4OS
Molecular Weight
427.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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