AM251
AM251 is a potent and selective cannabinoid receptor 1 (CB1) antagonist (IC50: 8 nM; Ki: 7.49 nM) with a 306-fold selectivity over CB2. It also acts as an effective GPR55 agonist (EC50: 39 nM) . This compound is widely used in vitro and in vivo to investigate the endocannabinoid system in metabolic, neurological, and pain research.
Product Specifications
CAS Number
183232-66-8
Product Name Alternative
AM 251, AM251, AM-251, Cannabinoid Receptor, CannabinoidReceptor, CB1, CB, inhibit, Inhibitor, GPR55
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Cannabinoid CB1 antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 13 mg/ml)
Smiles
CC1=C (N (N=C1C (NN2CCCCC2) =O) C3=C (Cl) C=C (Cl) C=C3) C4=CC=C (I) C=C4
Molecular Formula
C22H21Cl2IN4O
Molecular Weight
555.24
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (Piperidin-1-yl) -5- (4-iodophenyl) -1- (2,4-dichlorophenyl) -4-methyl-1H-pyrazole-3-carboxamide
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Monoclonal Antibody to Acetylcholinesterase (ACHE)
Monoclonal Antibody to Acetylcholinesterase (ACHE)
Monoclonal Antibody to Acetylcholinesterase (ACHE)
Monoclonal Antibody to Acetylcholinesterase (ACHE)