6BIO
GSK 3 Inhibitor IX (6-BIO) is a potent, ATP-competitive small molecule that selectively and reversibly inhibits GSK-3α/β (IC50=5 nM) and the CDK1-cyclin B complex. It is widely used in research to study Wnt/β-catenin signaling, neurodevelopment, and cellular proliferation in both in vitro and in vivo models.
Product Specifications
CAS Number
667463-62-9
Product Name Alternative
CDK5/p35, CDK1/CyclinB, CDK2/CyclinA, CDK, BIO, Apoptosis, 6-Bromoindirubin-3'-oxime, 6-bromoindirubin-3-oxime, 6-BIO, GSK-3, GSK3, GSK 3 Inhibitor IX, GSK 3 IX, MLS 2052, MLS2052, MLS-2052, Tyrosine Kinases, TyrosineKinases, Tyk2
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
GSK-3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 4 mg/ml with warming) .
Smiles
O\N=C1\C (\Nc2ccccc\12) =C1\C (=O) Nc2cc (Br) ccc12
Molecular Formula
C16H10BrN3O2
Molecular Weight
356.18
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2’Z,3’E) -6-Bromoindirubin-3’oxime
Available Sizes
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