Tenovin-1
Tenovin-1 is a small molecule inhibitor of the deacetylase enzymes SirT1 and SirT2. It stabilizes p53 by blocking its MDM2-mediated ubiquitination and degradation, making it a valuable tool for cancer research in both cellular and animal models.
Product Specifications
CAS Number
380315-80-0
Product Name Alternative
DHODH, degradation, Dihydroorotate Dehydrogenase, acetylation, Autophagy, inhibit, p53, Inhibitor, MDM2, Mdm2, MDM-2/p53, Tenovin 1, Tenovin1, Tenovin-1, protein-deacetylating, Sirtuin
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
SIRT1 and 2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up tp 10 mg/ml, warm)
Smiles
CC (=O) Nc1ccc (NC (=S) NC (=O) c2ccc (cc2) C (C) (C) C) cc1
Molecular Formula
C20H23N3O2S
Molecular Weight
369.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[ (4-Acetamidophenyl) carbamothioyl]-4-tert-butylbenzamide
Available Sizes
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