LDN-57444
LDN-57444 is a competitive and reversible inhibitor of the ubiquitin carboxyl-terminal hydrolase UCH-L1, exhibiting an IC50 of 0.88 μM. This small molecule is utilized in biochemical and cellular research to investigate proteasomal protein degradation pathways, including studies in models of neurodegenerative disease.
Product Specifications
CAS Number
668467-91-2
Product Name Alternative
UCH-L1, UCH-L3, Apoptosis, DUBs, Deubiquitinase, inhibit, Inhibitor, LDN57444, LDN-57444, LDN 57444
Field of Research
Cell Biology, Neuroscience, Protein Biochemistry
Purity
>98%
Bioactivity
DUB inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml) .
Smiles
CC (=O) ON=C1C (=O) N (Cc2cc (Cl) ccc2Cl) c2ccc (Cl) cc12
Molecular Formula
C17H11Cl3N2O3
Molecular Weight
397.65
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5-Chloro-1-[ (2,5-dichlorophenyl) methyl]-1H-indole-2,3-dione 3- (O-acetyloxime)
Available Sizes
Frequently Asked Questions
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