What is the catalog number for Sonidegib?

The catalog number for Sonidegib is orb1307090.

What sizes are available for Sonidegib?

Sonidegib is available in the following size(s): 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Sonidegib come in?

Sonidegib is available in 6 different pack sizes.

Is Sonidegib in stock?

Sonidegib is currently made to order / not held in immediate stock. Contact us for lead time.

Sonidegib

Sonidegib (Erismodegib) is a potent and selective Smoothened (Smo) antagonist that blocks Hedgehog (Hh) signaling, exhibiting IC50 values of 1.3 nM in mouse and 2.5 nM in human assays. This inhibitor is widely used in cancer research, particularly for studying basal cell carcinoma, in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

956697-53-3

Product Name Alternative

Sonidegib, Smoothened, Smo, Erismodegib, Inhibitor, Hedgehog, LDE 225, LDE225, LDE-225, NVP-LDE 225, NVP-LDE225, NVP-LDE-225, inhibit

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.3 mM) ; Ethanol:90 mg/mL (185.38 mM) ; DMSO:255 mg/mL (525.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)