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B-AP15 (NSC-687852)

B-AP15 (NSC-687852) is a selective small molecule inhibitor targeting the proteasomal deubiquitinases Usp14 and UCHL5. It is used in research to study proteasome function, protein degradation pathways, and has been investigated in vitro and in vivo for its potential effects in oncology and neurodegenerative disease models.

Product Specifications

CAS Number

1009817-63-3

Product Name Alternative

NSC-687852

Field of Research

Cell Biology, Protein Biochemistry

Purity

>98%

Bioactivity

DUB inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 35 mg/ml) .

Smiles

C (=C\1/C (=O) \C (=C\C2=CC=C (N (=O) =O) C=C2) \CN (C (C=C) =O) C1) \C3=CC=C (N (=O) =O) C=C3

Molecular Formula

C22H17N3O6

Molecular Weight

419.40

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

3,5-bis[ (4-Nitrophenyl) methylidene]-1-prop-2-enoylpiperidin-4-one

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