Bay 11-7085
Bay 11-7085 is a cell-permeable inhibitor that potently and irreversibly blocks TNFα-induced IκBα phosphorylation with an IC50 of 10 μM. It is widely used in vitro and in vivo to study NF-κB signaling in inflammation, immunology, and cancer research.
Product Specifications
CAS Number
196309-76-9
Product Name Alternative
Apoptosis, Bay 11 7085, BAY 11-7083, Bay 117085, BAY 11-7085, Bay 11-7085, inhibit, IκB, IκBα phosphorylation, NFkB, NF-kB, NFκB, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, Inhibitor, IKK, IkB/IKK, IkB, Ferroptosis
Field of Research
Cell Biology, Signal Transduction
Purity
99.43% (May vary between batches)
Solubility
DMSO:125 mg/mL (501.34 mM) ; Ethanol:24.9 mg/mL (99.87 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.02 mM)
Smiles
CC (C) (C) c1ccc (cc1) S (=O) (=O) \C=C\C#N
Molecular Formula
C13H15NO2S
Molecular Weight
249.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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