LDN193189
LDN193189 is a potent and selective BMP type I receptor inhibitor, primarily targeting ALK2 and ALK3. It is widely used in research on bone disorders like fibrodysplasia ossificans progressiva, with applications in both in vitro signaling studies and in vivo animal models of heterotopic ossification.
Product Specifications
CAS Number
1062368-24-4
Product Name Alternative
DM3189, DM-3189, DM 3189, ALK2, ALK3, LDN 193189, LDN193189, LDN-193189, inhibit, Inhibitor, Smad, Transforming growth factor beta receptors, TGF-β/Smad, TGFbeta/Smad, TGF-beta, TGF-β Receptor, TGFβ, TGFbeta, TGFb, TGF-b/Smad
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:1 mg/mL (2.46 mM) ; H2O:Insoluble;0.01M HCL:1.67 mg/mL (4.11 mM)
Smiles
C1CN (CCN1) c1ccc (cc1) -c1cnc2c (cnn2c1) -c1ccnc2ccccc12
Molecular Formula
C25H22N6
Molecular Weight
406.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6336341-01 0.1 mL
PPIL5, ID (LRR1, PPIL5, Leucine-rich repeat protein 1, 4-1BB-mediated-signaling molecule, 4-1BBlrr, LRR-repeat protein 1, Peptidylprolyl isomerase-like 5) (MaxLight 490)
Sign In for Pricing
View Details 
MBS6336341-02 5x 0.1 mL
PPIL5, ID (LRR1, PPIL5, Leucine-rich repeat protein 1, 4-1BB-mediated-signaling molecule, 4-1BBlrr, LRR-repeat protein 1, Peptidylprolyl isomerase-like 5) (MaxLight 490)
Sign In for Pricing
View Details 
H1827-56F 100 µg
HDAC8 (Histone Deacetylase 8, HD 8, HD8, CDA07, Histone Deacetylase-like 1, HDACL1) (Azide Free)
Sign In for Pricing
View Details 
TL711226V 500 µL Each
Rpl18 Rat shRNA Lentiviral Particle (Locus ID 81766)
Sign In for Pricing
View Details