LDN193189
LDN193189 is a potent and selective BMP type I receptor inhibitor, primarily targeting ALK2 and ALK3. It is widely used in research on bone disorders like fibrodysplasia ossificans progressiva, with applications in both in vitro signaling studies and in vivo animal models of heterotopic ossification.
Product Specifications
CAS Number
1062368-24-4
Product Name Alternative
DM3189, DM-3189, DM 3189, ALK2, ALK3, LDN 193189, LDN193189, LDN-193189, inhibit, Inhibitor, Smad, Transforming growth factor beta receptors, TGF-β/Smad, TGFbeta/Smad, TGF-beta, TGF-β Receptor, TGFβ, TGFbeta, TGFb, TGF-b/Smad
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:1 mg/mL (2.46 mM) ; H2O:Insoluble;0.01M HCL:1.67 mg/mL (4.11 mM)
Smiles
C1CN (CCN1) c1ccc (cc1) -c1cnc2c (cnn2c1) -c1ccnc2ccccc12
Molecular Formula
C25H22N6
Molecular Weight
406.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15084947 1 Vial
Lentiviral human EVA1C shRNA (UAS) - Lentiviral human EVA1C shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details 
RC209010L4 10 µg
Hairless (HR) (NM_005144) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details