Alectinib
Alectinib is a potent, selective, and orally bioavailable ATP-competitive inhibitor of ALK (IC50=1.9 nM) . It demonstrates robust antitumor activity in both cellular assays and animal models, underpinning its clinical application in ALK-positive non-small cell lung cancer (NSCLC) research.
Product Specifications
CAS Number
1256580-46-7
Product Name Alternative
CH5424802; RO5424802
Field of Research
Neuroscience
Purity
>99%
Bioactivity
ALK inhibitor, potent
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml) with warming
Smiles
CCc1cc2C (=O) c3c ([nH]c4cc (ccc34) C#N) C (C) (C) c2cc1N1CCC (CC1) N1CCOCC1
Molecular Formula
C30H34N4O2
Molecular Weight
482.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
9-Ethyl-6,6-dimethyl-8- (4-morpholin-4-ylpiperidin-1-yl) -11-oxo-5H-benzo[b]carbazole-3-carbonitrile
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