Spautin-1
Spautin-1 is a small molecule autophagy inhibitor that functions by targeting and inhibiting the deubiquitinases USP10 and USP13. It suppresses the unfolded protein response (UPR) and demonstrates selective toxicity toward cancer cells under glucose-deprived conditions, making it a useful research tool for studying autophagy, cancer metabolism, and cellular stress responses in vitro.
Product Specifications
CAS Number
1262888-28-7
Product Name Alternative
Spautin 1, Spautin1, Spautin-1, USP10, USP13, Apoptosis, Autophagy, inhibit, Inhibitor
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
USP10&13 inhibitor; autophagy inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming) .
Smiles
Fc1ccc (CNc2ncnc3ccc (F) cc23) cc1
Molecular Formula
C15H11F2N3
Molecular Weight
271.27
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6-Fluoro-N[ (4-fluorophenyl) methyl]-4-quinazolinamine
Available Sizes
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