SP-141
SP-141 is a small molecule MDM2 inhibitor that induces the target's auto-ubiquitination and proteasomal degradation. It demonstrates anticancer activity in vitro and has shown efficacy in reducing tumor growth in vivo in breast cancer and pancreatic cancer xenograft models.
Product Specifications
CAS Number
1253491-42-7
Product Name Alternative
Breast, degradation, auto-ubiquitination, cancer, pancreatic, inhibit, MDM-2/p53, Mdm2, Inhibitor, SP 141, SP141, SP-141
Field of Research
Cell Biology
Purity
98.01% (May vary between batches)
Solubility
DMSO:4.4 mg/mL (13.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.08 mM)
Smiles
COc1ccc2[nH]c3c (nccc3c2c1) -c1cccc2ccccc12
Molecular Formula
C22H16N2O
Molecular Weight
324.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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