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SP-141

SP-141 is a small molecule MDM2 inhibitor that induces the target's auto-ubiquitination and proteasomal degradation. It demonstrates anticancer activity in vitro and has shown efficacy in reducing tumor growth in vivo in breast cancer and pancreatic cancer xenograft models.

Product Specifications

CAS Number

1253491-42-7

Product Name Alternative

Breast, degradation, auto-ubiquitination, cancer, pancreatic, inhibit, MDM-2/p53, Mdm2, Inhibitor, SP 141, SP141, SP-141

Field of Research

Cell Biology

Purity

98.01% (May vary between batches)

Solubility

DMSO:4.4 mg/mL (13.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.08 mM)

Smiles

COc1ccc2[nH]c3c (nccc3c2c1) -c1cccc2ccccc12

Molecular Formula

C22H16N2O

Molecular Weight

324.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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