CGP 35348
CGP 35348 is a selective GABAB receptor antagonist (EC50 = 34 μM) . It is utilized in neuroscience research to investigate mechanisms of synaptic transmission and has been applied in studies examining neuromuscular coordination and spatial learning deficits in murine models of neonatal brain injury.
Product Specifications
CAS Number
123690-79-9
Product Name Alternative
Centrally, CGP35348, CGP-35348, CGP 35348, brain penetrant, active, Gamma-aminobutyric acid Receptor, GABAB, GABAReceptor, GABA Receptor, Inhibitor, inhibit, neuromuscular, neonatal damage, γ-Aminobutyric acid Receptor, spatial learning
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
≥98% (May vary between batches)
Solubility
DMSO:< 2.25 mg/mL (10 mM, insoluble or slightly soluble) ; H2O:41.66 mg/mL (184.97 mM)
Smiles
C (P (CCCN) (=O) O) (OCC) OCC
Molecular Formula
C8H20NO4P
Molecular Weight
225.22
Storage Conditions
-20°C
Notes
For research use only.
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