Pregnenolone Carbonitrile
Pregnenolone 16α-carbonitrile (PCN) is a well-characterized, potent agonist of the rodent pregnane X receptor (PXR) . Its primary research application is as a model inducer of CYP3A enzyme expression, facilitating studies of drug metabolism and nuclear receptor signaling in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
1434-54-4
Product Name Alternative
Pregnenolone Carbonitrile, Pregnenolone 16a-carbonitrile, Pregnenolone 16alpha-carbonitrile, Pregnenolone 16α-carbonitrile, Pregnenolone 16α-carbonitrile , Inhibitor, inhibit, orally, PXR, P4503A, cytochrome, Cytochrome P450, CYPs, CYP3A, 5-Pregnen-3beta-ol-20-one-16alpha-carbonitrile, 5-Pregnen-3b-ol-20-one-16a-carbonitrile, 5-Pregnen-3β-ol-20-one-16α-carbonitrile
Field of Research
Metabolism Research
Purity
99.64% (May vary between batches)
Solubility
DMSO:30 mg/mL (87.85 mM)
Smiles
[H][C@@]12C[C@@H] (C#N) [C@H] (C (C) =O) [C@@]1 (C) CC[C@@]1 ([H]) [C@@]2 ([H]) CC=C2C[C@@H] (O) CC[C@]12C
Molecular Formula
C22H31NO2
Molecular Weight
341.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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